ACTONEL (Risedronate)

ACTONEL, containing the active ingredient risedronate, is a prescription medication primarily used to treat and prevent osteoporosis in postmenopausal women and to increase bone mass in men with osteoporosis. This bisphosphonate works by inhibiting bone resorption, thereby helping to maintain or increase bone density, reducing the risk of fractures.

Key highlights of ACTONEL include:

• Indication: Effective in treating osteoporosis and preventing fractures in adults.


• Administration: Typically taken once a week or once a month, depending on the prescribed dosage.


• Mechanism of Action: Risedronate binds to bone surfaces, inhibiting osteoclast-mediated bone resorption.


• Side Effects: Some common side effects may include gastrointestinal discomfort, headache, and dizziness. Serious side effects can include jaw problems and atypical femur fractures.


• Contraindications: Not recommended for individuals with certain esophageal disorders, those who cannot sit or stand upright for at least 30 minutes, or those with low calcium levels.


• Drug Interactions: May interact with other medications, such as antacids and calcium supplements, so it is important to inform your healthcare provider of all medications you are taking.

Before starting ACTONEL, patients should discuss their complete medical history with their healthcare provider to ensure it is appropriate for their individual health needs. Regular monitoring and follow-up appointments are essential to assess the effectiveness of the treatment and manage any potential side effects.

• Risedronate sodium


• Microcrystalline cellulose


• Crospovidone


• Magnesium stearate


• Hydroxypropyl methylcellulose


• Triacetin

ACTONEL (Risedronate) is a medication used primarily to treat and prevent osteoporosis. To ensure effective use of this medication, follow these detailed instructions:

1. Consult Your Healthcare Provider: Before starting ACTONEL, discuss your medical history and any current medications with your doctor to ensure it is appropriate for you.


2. Dosage Instructions: Take ACTONEL exactly as prescribed by your healthcare provider. The usual dosage is one 35 mg tablet once a week, but your doctor may adjust this based on your specific condition.


3. Timing: It is best to take ACTONEL in the morning, at least 30 minutes before your first food or drink of the day.


4. Taking the Tablet: Swallow the tablet whole with a full glass (6 to 8 ounces) of plain water. Do not chew or suck on the tablet, as this can affect its effectiveness.


5. Post-Dosing Instructions: After taking ACTONEL, remain upright (sitting or standing) for at least 30 minutes. This helps to prevent any potential irritation to the esophagus.


6. Missing a Dose: If you forget to take a dose, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.


7. Hydration: Drink plenty of fluids throughout the day to stay hydrated, as this can help with the absorption of the medication.


8. Regular Check-ups: Schedule regular follow-up appointments with your healthcare provider to monitor your progress and any potential side effects.


9. Possible Side Effects: Be aware of potential side effects such as gastrointestinal discomfort, headache, or dizziness. Report any severe or persistent symptoms to your healthcare provider immediately.


10. Storage: Store ACTONEL at room temperature, away from moisture and heat. Keep the medication out of reach of children.


11. Do Not Stop Abruptly: Do not discontinue use without consulting your healthcare provider, as this may affect your bone health.

Always adhere to your healthcare provider's instructions and the information provided with the medication for the best results and to ensure your safety.