Xeljanz (Tofacitinib)

Xeljanz (Tofacitinib) is an oral medication that belongs to the class of Janus kinase (JAK) inhibitors. It is primarily used in the treatment of various autoimmune conditions, including rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. This innovative therapy works by selectively inhibiting the JAK enzymes, which play a crucial role in the inflammatory process, thereby reducing inflammation and preventing damage to the joints and tissues.

Some key highlights of Xeljanz include:

• Indications: Approved for adults with moderate to severe rheumatoid arthritis, active psoriatic arthritis, and moderate to severe ulcerative colitis.


• Mechanism of Action: Targets specific JAK enzymes to modulate immune response and decrease inflammation.


• Administration: Available in both immediate-release and extended-release formulations, allowing for flexible dosing options.


• Effectiveness: Clinical studies have demonstrated significant improvement in symptoms and functional outcomes for patients with autoimmune diseases.


• Safety Profile: Common side effects may include infections, changes in blood cell counts, and liver enzyme elevations; regular monitoring is recommended.


• Patient Considerations: Not suitable for individuals with certain infections, uncontrolled conditions, or those who have had a serious allergic reaction to the medication.

Xeljanz offers a new approach for individuals seeking relief from chronic autoimmune conditions, emphasizing the importance of personalized treatment plans and ongoing communication with healthcare providers.

• Tofacitinib


• Inactive ingredients:




• Lactose monohydrate


• Microcrystalline cellulose


• Magnesium stearate


• Hydroxypropyl methylcellulose


• Polyethylene glycol


• Titanium dioxide


• Iron oxide

Xeljanz, also known as tofacitinib, is a medication used to treat certain autoimmune conditions, including rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. To use Xeljanz effectively, follow these detailed instructions:

1. Consult Your Doctor: Before starting Xeljanz, discuss your medical history and any current medications with your healthcare provider. This ensures that Xeljanz is appropriate for your condition.


2. Dosage: Follow the prescribed dosage exactly as directed by your doctor. The typical starting dose for adults with rheumatoid arthritis is 5 mg taken orally twice a day. Your doctor may adjust your dosage based on your response to the medication.


3. Administration: Take Xeljanz by mouth with or without food. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.


4. Adherence: Take Xeljanz at the same times each day to maintain an even level of the medication in your system. Setting reminders can help you stay on track.


5. Missed Dose: If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up to make up for a missed dose.


6. Monitoring: Regular blood tests may be required to monitor your liver function and blood cell counts while on Xeljanz. Attend all scheduled appointments to ensure your safety.


7. Possible Side Effects: Be aware of potential side effects, which may include headache, diarrhea, or increased risk of infections. Contact your doctor if you experience severe side effects or signs of an allergic reaction.


8. Avoid Live Vaccines: While on Xeljanz, avoid live vaccines and inform your healthcare provider of any vaccinations you may need.


9. Storage: Store Xeljanz at room temperature, away from moisture and heat. Keep it out of reach of children and pets.

Always follow your healthcare provider's instructions and report any concerns or unusual symptoms while using Xeljanz. This will help ensure the best possible outcome in managing your condition.