Kombiglyze XR (Saxagliptin and Metformin) 5mg/500mg 28 Tablets (Saxagliptin 5mg and Metformin 500mg)

Kombiglyze XR is a prescription medication that combines two active ingredients, Saxagliptin and Metformin, to effectively manage blood sugar levels in adults with type 2 diabetes. This innovative formulation is designed to provide a dual-action approach, helping to improve glycemic control when diet and exercise alone are insufficient.

Saxagliptin, a DPP-4 inhibitor, works by increasing the levels of incretin hormones, which help to stimulate insulin release and decrease glucagon levels in the bloodstream. This action leads to improved blood sugar levels after meals. Metformin, on the other hand, primarily reduces glucose production in the liver and enhances insulin sensitivity, allowing the body to use glucose more effectively.

Key benefits of Kombiglyze XR include:

• Combination therapy that targets multiple pathways to control blood sugar.


• Extended-release formulation for once-daily dosing, promoting better adherence to treatment.


• Helps to reduce the risk of diabetes-related complications.


• May aid in weight management compared to some other diabetes medications.

Patients taking Kombiglyze XR should be aware of potential side effects, including gastrointestinal discomfort, and should consult their healthcare provider for personalized advice and monitoring. Regular blood sugar checks and lifestyle modifications are also recommended to optimize diabetes management.

Overall, Kombiglyze XR represents a valuable option for individuals seeking effective control of their type 2 diabetes through a combination of Saxagliptin and Metformin in a convenient, once-daily tablet form.

• Saxagliptin 5 mg


• Metformin 500 mg

Kombiglyze XR is a prescription medication that combines saxagliptin and metformin to help control blood sugar levels in adults with type 2 diabetes. It is important to follow the instructions provided by your healthcare provider when using this medication.

To use Kombiglyze XR effectively, adhere to the following guidelines:

1. Dosage: Take Kombiglyze XR exactly as prescribed by your doctor. The usual starting dose is one tablet taken once daily.


2. Timing: It is recommended to take the tablet with food to minimize gastrointestinal side effects. Choose a consistent time each day to take your medication.


3. Swallowing the Tablet: Take the tablet whole. Do not crush, chew, or split the tablet, as this may affect how the medication works.


4. Missed Dose: If you miss a dose, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once.


5. Monitoring Blood Sugar: Regularly check your blood sugar levels as instructed by your healthcare provider. This will help you and your doctor determine how well the medication is working.


6. Diet and Exercise: Maintain a balanced diet and engage in regular physical activity as recommended by your healthcare provider. This will enhance the effectiveness of Kombiglyze XR.


7. Potential Side Effects: Be aware of possible side effects, which may include nausea, diarrhea, or headaches. If you experience severe side effects or symptoms of low blood sugar, such as dizziness or confusion, contact your healthcare provider immediately.


8. Storage: Store Kombiglyze XR at room temperature, away from moisture and heat. Keep it out of reach of children.


9. Regular Check-ups: Schedule regular follow-up appointments with your healthcare provider to monitor your condition and adjust your treatment plan as necessary.

Always consult your healthcare provider for personalized advice and before making any changes to your treatment regimen. It is essential to use Kombiglyze XR as part of a comprehensive diabetes management plan.