COLY-MYCIN M INJECTION 1MIU vial (Colistimethate Sodium)

COLY-MYCIN M INJECTION 1MIU vial (Colistimethate Sodium)

Prescription only Generic
$134.47
Active Ingredient : Colistimethate Sodium
Meta description: Discover the benefits of COLY-MYCIN M INJECTION 1MIU vial, a powerful treatment option using Colistimethate Sodium to combat serious bacterial infections effectively. Ideal for healthcare professionals seeking reliable antibiotic solutio

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COLY-MYCIN M INJECTION 1MIU vial, containing Colistimethate Sodium, is a potent antibiotic formulated to combat severe infections caused by Gram-negative bacteria. It is particularly effective against strains resistant to other antibiotics, making it a critical option in clinical settings. This injection is commonly prescribed for infections such as pneumonia, urinary tract infections, and septicemia, where other treatments have proven ineffective.



The active ingredient, Colistimethate Sodium, belongs to the polymyxin class of antibiotics. It works by disrupting the bacterial cell membrane, leading to cell death. This mechanism ensures rapid action against susceptible organisms. The 1MIU vial is designed for intramuscular or intravenous administration, allowing flexibility in treatment based on the severity and type of infection.




  • Indications: Used for treating infections caused by susceptible Gram-negative bacteria, including Pseudomonas aeruginosa.

  • Dosage: Administered under medical supervision, with dosage tailored to the patient’s age, weight, and severity of the infection.

  • Precautions: Caution is advised in patients with renal impairment, as dosage adjustments may be necessary to avoid toxicity.

  • Side Effects: Potential side effects include nephrotoxicity, neurotoxicity, and allergic reactions. Close monitoring is essential during treatment.

  • Storage: Store in a cool, dry place, protected from light. Ensure the vial is intact before use.



COLY-MYCIN M INJECTION is a vital therapeutic option for multidrug-resistant infections, offering hope in challenging clinical scenarios. Always consult a healthcare professional for proper diagnosis, dosage, and administration to ensure safe and effective use.


  • Colistimethate Sodium

  • Sterile Water for Injection

COLY-MYCIN M INJECTION 1MIU vial (Colistimethate Sodium) is an antibiotic used to treat severe infections caused by certain types of bacteria. It is administered intravenously or intramuscularly and should only be used under the supervision of a healthcare professional.




  1. Preparation:

    • Ensure the vial and diluent are at room temperature before reconstitution.

    • Use sterile water for injection or normal saline (0.9% sodium chloride) as the diluent.

    • Add the recommended amount of diluent to the vial (usually 2–4 mL per 1 MIU vial) and swirl gently to dissolve the powder. Avoid shaking vigorously.

    • Inspect the solution for clarity. It should be clear and free of particles before use.




  2. Administration:

    • Intravenous (IV) Route:

      • Further dilute the reconstituted solution in 50–100 mL of compatible IV fluid (e.g., normal saline or 5% dextrose).

      • Administer as a slow IV infusion over 30–60 minutes.

      • Do not mix with other medications unless compatibility is confirmed.



    • Intramuscular (IM) Route:

      • Inject the reconstituted solution deep into a large muscle mass (e.g., gluteus or thigh).

      • Rotate injection sites to minimize discomfort.






  3. Dosage:

    • The dosage is determined by the severity of the infection, patient weight, and renal function.

    • Typical adult dose: 2.5–5 mg/kg/day (divided into 2–4 doses).

    • Renal impairment requires dosage adjustment based on creatinine clearance.

    • Follow the prescribing physician's instructions strictly.




  4. Precautions:

    • Monitor renal function and neurological symptoms during treatment.

    • Use with caution in patients with pre-existing kidney disease or neuromuscular disorders.

    • Discontinue if signs of hypersensitivity (rash, itching, difficulty breathing) occur.

    • Store unreconstituted vials at controlled room temperature (15–30°C).

    • Use reconstituted solution immediately or refrigerate for up to 24 hours.




  5. Disposal:

    • Discard any unused solution after the recommended storage period.

    • Dispose of needles and vials in a sharps container as per medical waste guidelines.





Always adhere to aseptic techniques during preparation and administration. Consult the product leaflet or a healthcare provider for further clarification.

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