BARACLUDE (Entecavir)

BARACLUDE (Entecavir) is an antiviral medication primarily used in the treatment of chronic hepatitis B virus (HBV) infection. This medication works by inhibiting the replication of the virus, thereby helping to reduce the viral load in the body and prevent liver damage.

Some key highlights of BARACLUDE include:

• Mechanism of Action: Entecavir is a nucleoside analogue that specifically targets the reverse transcriptase enzyme of HBV, effectively blocking the virus's ability to multiply.


• Indications: It is prescribed for adults and pediatric patients aged 2 years and older with chronic HBV infection who have evidence of active viral replication and elevated liver enzyme levels.


• Dosing: The typical recommended dose for adults is 0.5 mg once daily, with adjustments made for patients with renal impairment.


• Side Effects: Common side effects may include headache, fatigue, dizziness, and nausea. Serious side effects can occur, including lactic acidosis and severe liver problems, which require immediate medical attention.


• Resistance: Patients may develop resistance to BARACLUDE, particularly if the medication is not taken as directed. Regular monitoring of liver function and viral load is essential during treatment.


• Pregnancy and Nursing: The safety of BARACLUDE during pregnancy and breastfeeding has not been fully established, so it should be used only if the potential benefits outweigh the risks.


• Drug Interactions: BARACLUDE may interact with other medications, so it's crucial for patients to inform their healthcare provider about all drugs they are taking.

Overall, BARACLUDE is a vital option for managing chronic hepatitis B, offering hope for patients seeking to control their infection and maintain liver health.

• Entecavir


• Microcrystalline cellulose


• Croscarmellose sodium


• Hydroxypropyl cellulose


• Magnesium stearate


• Opadry II White (contains: Polyvinyl alcohol, Talc, Titanium dioxide, and other components)

BARACLUDE (Entecavir) is an antiviral medication used primarily to treat chronic hepatitis B virus infection. It is essential to follow the prescribed guidelines for optimal results and to minimize potential side effects.

Before starting treatment, consult your healthcare provider to ensure that BARACLUDE is appropriate for your condition. Inform them of any other medications you are taking, as well as your complete medical history.

When using BARACLUDE, adhere to the following instructions:

1. Dosage: Take BARACLUDE exactly as prescribed by your healthcare provider. The typical dose for adults is 0.5 mg or 1 mg once daily, depending on your medical history and kidney function.


2. Administration: You can take BARACLUDE with or without food. However, it is recommended to take it consistently with regard to meals to maintain even levels of the medication in your body.


3. Missed Dose: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at once.


4. Regular Monitoring: Keep regular appointments with your healthcare provider to monitor your liver function and response to the treatment. Blood tests may be necessary to check for any changes in your condition.


5. Adverse Effects: Be aware of potential side effects, which may include headache, fatigue, dizziness, or nausea. Contact your healthcare provider if you experience severe side effects or signs of an allergic reaction.


6. Do Not Share: Do not share your medication with others, even if they have similar symptoms. BARACLUDE is prescribed based on your specific health needs.


7. Storage: Store BARACLUDE at room temperature, away from moisture and heat. Keep it out of reach of children and pets.

If you have any questions or concerns about using BARACLUDE, do not hesitate to reach out to your healthcare provider for further clarification and support. Following these guidelines can help ensure that you receive the most benefit from your treatment.