ARTANE (Trihexyphenidyl)

ARTANE, known generically as Trihexyphenidyl, is a medication primarily used to treat symptoms of Parkinson's disease and to manage drug-induced extrapyramidal symptoms, such as those caused by antipsychotic medications. This anticholinergic agent works by balancing neurotransmitters in the brain, particularly acetylcholine, which helps reduce muscle stiffness, tremors, and spasms.

Some key highlights of ARTANE include:

• Mechanism of Action: Trihexyphenidyl acts by blocking acetylcholine receptors, thereby reducing the overactivity of the nervous system that can lead to motor symptoms.


• Indications: It is primarily prescribed for Parkinson's disease and to treat akathisia, a condition characterized by a feeling of inner restlessness.


• Dosing: The dosage of ARTANE is individualized based on patient response and tolerance, typically starting low and gradually increasing.


• Side Effects: Common side effects may include dry mouth, blurred vision, constipation, and dizziness. Patients should be monitored for any severe reactions.


• Precautions: Caution is advised in patients with glaucoma, urinary retention, or gastrointestinal obstruction. It's essential to inform healthcare providers of all medical history and current medications.


• Drug Interactions: ARTANE may interact with other medications, especially other anticholinergics, antihistamines, and certain antidepressants, which can enhance side effects.


• Patient Education: Patients should be educated on the importance of adherence to their prescribed regimen and advised to report any unusual symptoms or side effects promptly.

Overall, ARTANE can be an effective component of a comprehensive treatment plan for managing Parkinson's disease and related symptoms, but it requires careful consideration and monitoring by healthcare professionals.

• Trihexyphenidyl hydrochloride


• Microcrystalline cellulose


• Lactose monohydrate


• Corn starch


• Magnesium stearate

ARTANE, which contains the active ingredient trihexyphenidyl, is commonly prescribed to help control symptoms of Parkinson's disease or to counteract side effects of certain medications. To use ARTANE effectively, follow these instructions carefully.

1. Consult with your healthcare provider before starting ARTANE. Discuss your medical history and any other medications you are currently taking to avoid potential interactions.




2. Take ARTANE exactly as prescribed. It is typically taken by mouth, with or without food. Follow your doctor’s instructions on the dosage and frequency.




3. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet, as this can affect how the medication is absorbed.




4. Try to take ARTANE at the same time each day to help establish a routine and improve adherence to your medication schedule.




5. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.




6. Be aware of potential side effects, which may include dry mouth, blurred vision, constipation, or dizziness. If you experience any severe side effects or an allergic reaction, contact your healthcare provider immediately.




7. Do not stop taking ARTANE abruptly without consulting your doctor, as this may worsen your symptoms. Your doctor will provide guidance on how to safely discontinue the medication if necessary.




8. Keep all follow-up appointments with your healthcare provider to monitor your response to the medication and make any necessary adjustments to your treatment plan.

Always store ARTANE at room temperature, away from moisture and heat, and keep it out of reach of children. This medication should only be used by the individual for whom it was prescribed.