Xeljanz (Tofacitinib)

Xeljanz (Tofacitinib) is an oral medication primarily used to treat various autoimmune conditions, including rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It belongs to a class of drugs known as Janus kinase (JAK) inhibitors, which work by interfering with the inflammatory processes in the body.

Some key highlights of Xeljanz include:

• Mechanism of Action: Xeljanz inhibits JAK enzymes, which play a crucial role in the signaling pathways that lead to inflammation and immune responses. By blocking these pathways, it helps reduce symptoms and improve the quality of life for patients.


• Efficacy: Clinical studies have shown that Xeljanz can significantly reduce disease activity, improve physical function, and enhance overall well-being in patients with rheumatoid arthritis and other conditions.


• Administration: Xeljanz is available in both immediate-release and extended-release formulations, making it convenient for patients to integrate into their daily routines.


• Side Effects: Common side effects may include headaches, upper respiratory infections, and gastrointestinal issues. Patients should be monitored for potential serious side effects, including infections and blood clots.


• Considerations: Prior to starting Xeljanz, patients should discuss their medical history with their healthcare provider, especially if they have a history of infections, liver problems, or are taking other medications that affect the immune system.

Overall, Xeljanz represents a significant advancement in the treatment of autoimmune diseases, offering patients an effective oral alternative to traditional therapies. As with any medication, it is essential for patients to work closely with their healthcare providers to determine the best treatment plan tailored to their needs.

• Tofacitinib


• Inactive ingredients:




• Microcrystalline cellulose


• Hypromellose


• Lactose monohydrate


• Magnesium stearate


• Colloidal silicon dioxide


• Film coating (hypromellose, titanium dioxide, polyethylene glycol)

Xeljanz, or tofacitinib, is an oral medication used primarily to treat certain autoimmune conditions such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It is essential to follow your healthcare provider's instructions when using this medication.

Before starting Xeljanz, ensure that you discuss your complete medical history with your doctor, including any current medications, allergies, and pre-existing conditions. This will help prevent potential drug interactions and side effects.

To use Xeljanz effectively, follow these steps:

1. Dosage: Take Xeljanz exactly as prescribed by your healthcare provider. The typical starting dose may vary based on your condition. For rheumatoid arthritis and psoriatic arthritis, it is often 5 mg taken twice daily, while for ulcerative colitis, the dosage may differ.


2. Administration: Swallow the tablet whole with a glass of water. You can take it with or without food, but try to take it at the same time each day to maintain a consistent routine.


3. Missed Dose: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once to make up for a missed dose.


4. Monitoring: Regular check-ups with your healthcare provider are essential while on Xeljanz. They may order blood tests to monitor your liver function, blood cell counts, and cholesterol levels.


5. Side Effects: Be aware of potential side effects, which may include headache, nausea, or increased risk of infections. Contact your doctor immediately if you experience severe side effects like shortness of breath, chest pain, or unusual bruising.


6. Storage: Store Xeljanz at room temperature, away from moisture and heat. Keep it out of reach of children and pets.

Always consult your healthcare provider before making any changes to your medication regimen or if you have any questions or concerns about using Xeljanz.