Simbrinza Ophthalmic Suspension (Brinzolamide (1% w/v) + Brimonidine (0.2% w/v))

Simbrinza Ophthalmic Suspension combines two active ingredients: Brinzolamide (1% w/v) and Brimonidine (0.2% w/v). This unique formulation is designed to effectively lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Brinzolamide is a carbonic anhydrase inhibitor that works by decreasing the production of intraocular fluid, while Brimonidine is an alpha agonist that reduces fluid production and increases drainage. Together, they provide a dual mechanism of action, making Simbrinza a powerful option for managing eye pressure.

One of the key advantages of Simbrinza is its preservative-free formulation, which minimizes irritation and is suitable for patients with sensitive eyes. The convenient suspension form allows for easy administration, ensuring that patients can easily incorporate it into their daily routine.

Clinical studies have shown that Simbrinza effectively reduces intraocular pressure, which is crucial for preventing damage to the optic nerve and preserving vision over time. It is typically used when other treatments are not sufficient or when patients prefer a combination therapy.

Patients should follow their healthcare provider's instructions regarding dosage and administration. Common side effects may include eye discomfort, dry mouth, and fatigue, though these are generally mild. Always consult with a healthcare professional before starting any new medication to ensure it is appropriate for your specific condition.

In summary, Simbrinza Ophthalmic Suspension offers an effective and convenient option for managing intraocular pressure in glaucoma and ocular hypertension patients, enhancing both treatment adherence and patient comfort.

• Brinzolamide (1% w/v)


• Brimonidine (0.2% w/v)

Simbrinza Ophthalmic Suspension is a combination medication used to lower intraocular pressure in individuals with open-angle glaucoma or ocular hypertension. Follow these detailed instructions for proper use:

1. Before using the medication, wash your hands thoroughly with soap and water to prevent contamination.




2. Shake the bottle gently to ensure the suspension is well mixed.




3. Remove the cap from the bottle, taking care not to touch the dropper tip to any surface, including your hands or eyes.




4. Tilt your head back slightly and look upward. With your index finger, pull down your lower eyelid to create a small pocket.




5. Hold the bottle upside down and squeeze it gently to release one drop of the suspension into the pocket of your lower eyelid. Avoid touching the eye or eyelid with the dropper tip.




6. Close your eye gently for a few minutes to allow the medication to be absorbed. Do not blink or squeeze your eye shut.




7. If you are using other eye drops, wait at least 5 to 10 minutes before applying them to avoid washing out the medication.




8. After using the drops, replace the cap on the bottle securely. Do not rinse or wipe the dropper tip.




9. Store the medication at room temperature, away from light and moisture. Do not freeze.




10. Keep the product out of reach of children and do not use it after the expiration date indicated on the packaging.




11. If you experience any discomfort, redness, or vision changes after using the drops, contact your healthcare provider for advice.

Adhering to these instructions will help ensure the effective use of Simbrinza Ophthalmic Suspension for managing your eye condition. Always follow your healthcare provider's recommendations regarding dosage and frequency of use.