PREZISTA (Darunavir) (Darunavir)

PREZISTA (Darunavir) is an antiretroviral medication used in the treatment of HIV-1 infection. This medication is part of the class of drugs known as protease inhibitors, which play a crucial role in managing HIV by preventing the virus from replicating in the body.

Key highlights of PREZISTA include:

• Mechanism of Action: PREZISTA works by inhibiting the protease enzyme, which is essential for the HIV virus to replicate and produce new viral particles. This action helps to reduce the viral load in the body.


• Combination Therapy: PREZISTA is often used in combination with other antiretroviral agents to enhance its effectiveness and provide a comprehensive treatment approach for HIV.


• Resistance Profile: PREZISTA has a high barrier to resistance, making it effective even in patients with a history of treatment failure or resistance to other protease inhibitors.


• Administration: It is typically taken once or twice daily with food, which aids in its absorption and effectiveness.


• Side Effects: Common side effects may include nausea, diarrhea, headache, and fatigue. Most side effects are manageable and diminish over time.


• Monitoring: Regular monitoring of liver function and viral load is recommended during treatment to ensure efficacy and safety.


• Patient Considerations: PREZISTA is not suitable for everyone. It's essential for patients to discuss their medical history and any other medications they are taking with their healthcare provider to avoid potential interactions.

Overall, PREZISTA (Darunavir) is a vital medication for individuals living with HIV, offering effective viral suppression and a favorable resistance profile, contributing to improved health outcomes.

• Darunavir


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PREZISTA (Darunavir) is an antiretroviral medication used to treat HIV infection. It is important to follow the prescribed instructions carefully to ensure the effectiveness of the treatment.

Before starting PREZISTA, consult your healthcare provider to discuss your medical history and any medications you are currently taking, as interactions can occur. Make sure to inform your doctor if you have any liver problems or if you are pregnant or breastfeeding.

To use PREZISTA:

1. Dosage: Take PREZISTA exactly as prescribed by your healthcare provider. The usual dose for adults is 800 mg once daily, taken with food. Follow your doctor's guidance regarding dosage adjustments.


2. Administration: Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet, as this may affect how the medication works.


3. Timing: Take PREZISTA at the same time each day to help remember your dose. Consistency is key in maintaining effective drug levels in your body.


4. Missed Dose: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.


5. Food: Always take PREZISTA with food to enhance absorption and effectiveness. A meal can help improve the medication's performance.


6. Alcohol and Drug Interactions: Avoid alcohol and inform your healthcare provider about all other medications, including over-the-counter drugs and herbal supplements, to prevent potential interactions.


7. Regular Monitoring: Attend regular follow-up appointments with your healthcare provider to monitor your progress and adjust your treatment plan as needed.


8. Side Effects: Be aware of potential side effects such as nausea, diarrhea, or rash. Contact your healthcare provider if you experience severe or persistent side effects.

It is crucial to adhere to the treatment regimen and not to stop taking PREZISTA without consulting your healthcare provider, as this may lead to drug resistance and treatment failure.