Nexletol (Bampedoic Acid )

Nexletol (Bempedoic Acid) is a prescription medication designed to help lower cholesterol levels in adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease. It works by inhibiting ATP citrate lyase, an enzyme involved in the cholesterol synthesis pathway, thus reducing the production of cholesterol in the liver.

Key highlights of Nexletol include:

• Effective in lowering low-density lipoprotein cholesterol (LDL-C) levels, particularly when used in conjunction with a healthy diet.


• Can be used as an adjunct to maximally tolerated statin therapy or in patients who are statin-intolerant.


• Administered orally, typically once daily, offering convenience for patients.


• Clinical studies have demonstrated significant reductions in LDL-C levels, contributing to improved cardiovascular health.


• May provide additional cardiovascular benefits beyond cholesterol reduction.


• Common side effects may include muscle spasms, abdominal pain, and increased liver enzymes; monitoring is recommended.


• Not recommended for use in patients with severe liver impairment.

As with any medication, it is essential to discuss potential risks and benefits with a healthcare provider to determine if Nexletol is the right choice for managing cholesterol levels effectively.

• Bempedoic acid


• Microcrystalline cellulose


• Croscarmellose sodium


• Magnesium stearate


• Hydroxypropyl cellulose


• Silicon dioxide


• Film coating


• Polyvinyl alcohol


• Talc


• Triacetin


• Iron oxide red


• Iron oxide yellow

Nexletol (Bempedoic Acid) is a prescription medication used to help lower cholesterol levels in adults with certain conditions. It is important to follow your healthcare provider’s instructions when using this medication. Here are the steps to properly use Nexletol:

1. Consult your healthcare provider to ensure that Nexletol is appropriate for you. Discuss your medical history and any other medications you are currently taking.




2. Take Nexletol exactly as prescribed. The typical dosage is one tablet taken once daily, with or without food. Do not exceed the recommended dose.




3. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication works.




4. If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not take two doses at the same time.




5. Continue to take Nexletol regularly to maintain its cholesterol-lowering effects. Set a reminder if necessary to help you remember your daily dose.




6. Monitor your cholesterol levels as directed by your healthcare provider. Regular blood tests may be necessary to assess your progress and adjust your treatment if needed.




7. Be aware of potential side effects, such as muscle pain, tenderness, or weakness. Contact your healthcare provider if you experience any unusual symptoms or if you have concerns about your treatment.




8. Maintain a healthy lifestyle, including a balanced diet and regular exercise, to enhance the effectiveness of Nexletol in managing your cholesterol levels.




9. Store Nexletol at room temperature, away from moisture and heat. Keep it out of reach of children and pets.

Always follow the guidance of your healthcare provider and do not hesitate to reach out if you have questions or need further clarification regarding your treatment with Nexletol.