MAKENA INJECTION 250mg syr (Hydroxyprogesterone)

MAKENA INJECTION is a medication that contains Hydroxyprogesterone, specifically formulated to help reduce the risk of preterm birth in women who have a history of spontaneous preterm delivery. This injectable solution provides essential hormonal support during pregnancy, particularly for those at increased risk.

Here are some key highlights of MAKENA INJECTION:

• Indication: Designed for use in pregnant women with a history of preterm birth, MAKENA helps to prolong pregnancy and improve outcomes for both mother and baby.


• Administration: The injection is typically administered once a week by a healthcare professional, ensuring proper dosage and monitoring of the patient.


• Mechanism of Action: Hydroxyprogesterone works by stabilizing the uterine lining and reducing uterine contractions, which can help prevent early labor.


• Safety Information: It is important for patients to discuss their medical history and any other medications they are taking with their healthcare provider to avoid potential interactions and side effects.


• Monitoring: Regular follow-up appointments are crucial to monitor the health of both the mother and the fetus during treatment with MAKENA.


• Potential Side Effects: Common side effects may include injection site reactions, headaches, and nausea, but it is important to report any unusual symptoms to a healthcare provider immediately.

MAKENA INJECTION represents a significant advancement in prenatal care, offering hope and support to women at risk of preterm labor. Always consult with your healthcare provider for personalized medical advice and to determine if MAKENA is the right choice for your pregnancy journey.

• Hydroxyprogesterone caproate


• Castor oil


• Glycerin


• Polysorbate 80


• Cholesterol


• Hydrochloric acid (for pH adjustment)


• Sodium hydroxide (for pH adjustment)


• Water for injection

MAKENA INJECTION (Hydroxyprogesterone) is typically prescribed to reduce the risk of preterm birth in women who have a history of preterm labor. Proper usage is essential for effectiveness and safety. Follow these detailed instructions to ensure correct administration:

1. Consult Your Healthcare Provider: Before starting the injection, discuss with your healthcare provider to understand the dosage and frequency tailored to your specific needs.



2. Preparation: Gather all necessary supplies, including the MAKENA injection vial, a sterile syringe, alcohol swabs, and a sharps disposal container.



3. Wash Your Hands: Thoroughly wash your hands with soap and water to prevent infection.



4. Prepare the Injection Site: Choose an injection site, typically the upper outer quadrant of the buttock. Clean the area with an alcohol swab and let it dry.



5. Draw the Medication: Remove the cap from the vial and wipe the rubber stopper with an alcohol swab. Pull back the plunger of the syringe to the prescribed dosage, insert the needle into the vial, and push the plunger to inject air into the vial. Then, invert the vial and draw the prescribed amount of medication into the syringe.



6. Remove Air Bubbles: Tap the syringe gently to move any air bubbles to the top and push the plunger slightly to expel the air.



7. Inject the Medication: Hold the syringe like a dart, insert the needle at a 90-degree angle into the cleaned injection site, and push the plunger slowly to inject the medication.



8. Withdraw the Needle: Once the medication is injected, withdraw the needle quickly and apply gentle pressure to the injection site with a clean cotton ball or gauze.



9. Dispose of Materials: Safely dispose of the needle and syringe in a sharps container. Do not reuse needles or syringes.



10. Monitor for Side Effects: After the injection, observe for any adverse reactions such as pain at the injection site, dizziness, or allergic reactions. Contact your healthcare provider if you experience any concerning symptoms.

Always follow your healthcare provider's instructions regarding the dosage and schedule of MAKENA injections, and do not hesitate to reach out to them with any questions or concerns regarding your treatment.