EMEND (Aprepitant)

EMEND (Aprepitant) is a prescription medication primarily used to prevent nausea and vomiting caused by chemotherapy, as well as to treat postoperative nausea and vomiting. It belongs to a class of drugs known as neurokinin-1 (NK1) receptor antagonists, which work by blocking the action of substance P, a neuropeptide associated with the vomiting reflex.

This medication is often prescribed in combination with other antiemetic agents, enhancing its effectiveness in managing nausea. EMEND is available in both oral and injectable forms, providing flexibility in administration based on patient needs and circumstances.

Some important highlights about EMEND include:

• Indications: Effective for preventing nausea and vomiting associated with highly emetogenic cancer chemotherapy and for preventing postoperative nausea and vomiting.


• Dosage: Typically administered as a three-day regimen, starting with a loading dose on the day of chemotherapy, followed by two additional doses on subsequent days.


• Side Effects: Common side effects may include fatigue, diarrhea, constipation, and loss of appetite. Serious side effects are rare but can occur.


• Drug Interactions: EMEND can interact with various medications, including hormonal contraceptives and certain anticoagulants. It's important to inform your healthcare provider of all medications you are taking.


• Patient Considerations: Caution is advised in patients with liver impairment, and dosing adjustments may be necessary.

Overall, EMEND (Aprepitant) is a valuable option for patients undergoing chemotherapy or recovering from surgery, aiming to improve their quality of life by effectively managing nausea and vomiting.

• Aprepitant


• Corn Starch


• Microcrystalline Cellulose


• Magnesium Stearate


• Gelatin


• Iron Oxide Red


• Iron Oxide Yellow


• Titanium Dioxide

EMEND (Aprepitant) is a medication used to prevent nausea and vomiting caused by chemotherapy or surgery. To use EMEND effectively, follow these detailed instructions:

1. Consult your healthcare provider to ensure EMEND is appropriate for you, especially if you have any existing medical conditions or are taking other medications.




2. Take EMEND exactly as prescribed. The typical dosage for adults is usually 125 mg taken orally on the first day of chemotherapy, followed by 80 mg once daily on the next two days.




3. Swallow the capsule whole with a full glass of water. Do not chew or break the capsule.




4. It is recommended to take EMEND at least one hour before the start of chemotherapy treatment.




5. If you miss a dose, take it as soon as you remember on the same day. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once.




6. Maintain a record of your medication schedule to avoid missed doses and ensure consistent use.




7. Be aware of potential side effects, which may include fatigue, constipation, and loss of appetite. Report any severe side effects or allergic reactions to your healthcare provider immediately.




8. Keep EMEND in its original container, tightly closed, and store it at room temperature away from moisture and heat.




9. Do not share this medication with others, even if they have similar symptoms, as it is prescribed specifically for your use.




10. Attend all follow-up appointments with your healthcare provider to monitor your response to the medication and make any necessary adjustments.

By adhering to these instructions, you can maximize the effectiveness of EMEND in managing nausea and vomiting associated with chemotherapy or surgery.