Cibinqo (Abrocitinib)

Cibinqo (Abrocitinib) is a prescription medication designed to treat moderate to severe atopic dermatitis, also known as eczema, in adults and certain pediatric patients. It functions as a selective Janus kinase (JAK) inhibitor, which helps to reduce inflammation and alleviate symptoms associated with this chronic skin condition.

Here are some key highlights of Cibinqo:

• Mechanism of Action: Cibinqo selectively inhibits JAK1, a key enzyme involved in the inflammatory process, thereby reducing the production of pro-inflammatory cytokines.


• Indication: Approved for use in adults and adolescents aged 12 years and older who are candidates for systemic therapy.


• Dosing: Typically taken once daily, with or without food, allowing for flexibility in administration.


• Efficacy: Clinical studies have shown significant improvement in skin clearance and reduction of itch compared to placebo, enhancing patients' quality of life.


• Side Effects: Common side effects may include nausea, headache, and increased risk of infections, necessitating monitoring during treatment.


• Long-term Use: Ongoing studies are assessing the long-term safety and efficacy of Cibinqo, providing valuable insights for both patients and healthcare providers.


• Patient Support: A range of resources and support programs are available to assist patients in managing their condition and navigating treatment options.

Cibinqo represents a significant advancement in the treatment of atopic dermatitis, offering hope to those seeking relief from the challenges posed by this condition.

• Abrocitinib


• Inactive ingredients


• Microcrystalline cellulose


• Hypromellose


• Magnesium stearate


• Colloidal silicon dioxide


• Other excipients as necessary

Cibinqo (Abrocitinib) is a medication primarily used for the treatment of moderate to severe atopic dermatitis in adults and pediatric patients aged 12 years and older. To ensure safe and effective use, it is important to follow the instructions provided by your healthcare provider.

Before starting treatment with Cibinqo, make sure to inform your doctor of your complete medical history, including any allergies or other medications you are currently taking. Your doctor will determine the appropriate dosage based on your condition and overall health.

1. Dosage: Take Cibinqo exactly as prescribed by your healthcare provider. The usual starting dose for adults is 100 mg once daily. Depending on your response and tolerance, your doctor may adjust the dosage.


2. Administration: Cibinqo should be taken orally, with or without food. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.


3. Missed Dose: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.


4. Monitoring: Regular follow-up appointments with your healthcare provider are essential. They will monitor your response to the medication and check for any potential side effects.


5. Side Effects: Be aware of possible side effects, which may include nausea, headache, fatigue, or increased risk of infections. Report any severe or unusual symptoms to your healthcare provider immediately.


6. Storage: Store Cibinqo at room temperature, away from moisture and heat. Keep it out of reach of children and pets.

Always read the patient information leaflet provided with the medication for additional details and consult your healthcare provider for any questions or concerns regarding your treatment with Cibinqo.