BIDIL (Isosorbide dinitrate/Hydralazine)

BIDIL is a prescription medication that combines two active ingredients: isosorbide dinitrate and hydralazine. This unique formulation is specifically designed to treat heart failure in certain populations, particularly African American patients. It works by relaxing blood vessels, which helps to improve blood flow and reduce the workload on the heart.

Key highlights of BIDIL include:

• Dual Action: The combination of isosorbide dinitrate and hydralazine provides a synergistic effect, improving heart function more effectively than either drug alone.


• Targeted Treatment: BIDIL is particularly beneficial for African American patients with heart failure, as studies have shown improved outcomes in this demographic.


• Dosage Flexibility: The medication allows for tailored dosing to meet individual patient needs, ensuring optimal therapeutic effects.


• Improved Quality of Life: By alleviating symptoms of heart failure, BIDIL can enhance the overall quality of life for patients, enabling them to engage in daily activities with greater ease.


• Clinical Evidence: BIDIL has been supported by clinical trials demonstrating its efficacy in reducing mortality and hospitalizations related to heart failure.


• Side Effects: While generally well-tolerated, patients may experience side effects such as headache, dizziness, or hypotension, which should be monitored by healthcare providers.

Before starting BIDIL, it is essential for patients to discuss their medical history and any other medications they are taking with their healthcare provider to avoid potential interactions and ensure safe use.

• Isosorbide dinitrate


• Hydralazine

BIDIL is a prescription medication that combines isosorbide dinitrate and hydralazine. It is primarily used to treat heart failure in certain patients. To use BIDIL effectively, follow these detailed instructions:

1. Consult Your Doctor: Before starting BIDIL, consult your healthcare provider to ensure it is appropriate for your condition and to discuss any potential interactions with other medications you might be taking.


2. Follow Prescribed Dosage: Take BIDIL exactly as prescribed by your doctor. Typically, it is taken two to three times a day. Do not adjust the dosage without consulting your healthcare provider.


3. Administration: Swallow the tablets whole with a glass of water. Do not crush or chew the tablets, as this may affect how the medication is absorbed by your body.


4. Timing: It is advisable to take BIDIL at the same times each day to maintain an even level of the medication in your bloodstream. This consistency helps in managing your condition effectively.


5. Avoid Alcohol: Limit or avoid alcohol consumption while taking BIDIL, as alcohol can increase the risk of side effects like dizziness or fainting.


6. Monitor Side Effects: Be aware of possible side effects, including headaches, dizziness, or low blood pressure. If you experience severe side effects or signs of an allergic reaction, seek medical attention immediately.


7. Regular Check-ups: Attend regular follow-up appointments with your healthcare provider to monitor your progress and make any necessary adjustments to your treatment plan.


8. Store Properly: Keep BIDIL in a cool, dry place away from light and moisture. Ensure it is out of reach of children and pets.


9. Do Not Discontinue Abruptly: If you need to stop taking BIDIL, consult your doctor for a proper tapering plan to avoid withdrawal symptoms.

By following these instructions, you can use BIDIL safely and effectively to manage your heart failure symptoms. Always prioritize open communication with your healthcare team for the best outcomes.