BARACLUDE (Entecavir)

BARACLUDE (Entecavir) is an antiviral medication primarily used for the treatment of chronic hepatitis B virus (HBV) infection. It works by inhibiting the replication of the virus, thus helping to reduce the viral load in the body and improving liver function.

Key highlights of BARACLUDE include:

• Indication: BARACLUDE is prescribed for adults and pediatric patients aged 2 years and older with chronic hepatitis B who have evidence of active viral replication and liver inflammation.


• Mechanism of Action: The active ingredient, Entecavir, is a nucleoside analog that competes with the natural substrate for incorporation into viral DNA, effectively stopping the virus from multiplying.


• Dosing: The recommended dosage may vary based on the patient's age, weight, and renal function. It is typically taken once daily, with or without food.


• Effectiveness: Clinical studies have shown that BARACLUDE can significantly lower HBV DNA levels, improve liver histology, and reduce the risk of liver-related complications.


• Side Effects: Common side effects may include headache, fatigue, dizziness, and nausea. Serious side effects could involve lactic acidosis and liver problems, particularly if treatment is stopped suddenly.


• Resistance: Resistance to Entecavir can develop in patients who have previously been treated with other antiviral medications. Regular monitoring is essential to assess the effectiveness of treatment.


• Precautions: Patients with a history of kidney disease or those undergoing dialysis should use BARACLUDE with caution, as it may require dosage adjustments.


• Drug Interactions: BARACLUDE may interact with other medications, so it's important for patients to inform their healthcare provider about all the drugs they are taking.

Overall, BARACLUDE offers a valuable treatment option for those suffering from chronic hepatitis B, helping to manage the infection effectively while minimizing potential complications associated with the disease.

• Entecavir


• Inactive ingredients:




• Microcrystalline cellulose


• Magnesium stearate


• Crospovidone


• Hydroxypropyl cellulose


• Silicon dioxide


• Film coating (Opadry II Blue 85F15114)


• Polyvinyl alcohol


• Titanium dioxide


• Macrogol 3350


• Iron oxide

BARACLUDE (Entecavir) is an antiviral medication used primarily to treat chronic hepatitis B virus infections. It is crucial to follow your healthcare provider's instructions when using this medication to ensure its effectiveness and minimize potential side effects.

Here are the steps to properly use BARACLUDE:

1. Consult Your Doctor: Before starting BARACLUDE, discuss your medical history and any other medications you are taking with your healthcare provider. They will determine if BARACLUDE is appropriate for you.


2. Take as Prescribed: Follow the dosage prescribed by your doctor. BARACLUDE is usually taken once daily. Do not take more or less than directed.


3. Timing: Take BARACLUDE on an empty stomach, either at least 2 hours before or 2 hours after a meal. This helps increase absorption and effectiveness.


4. Swallow Whole: Take the tablet whole with a glass of water. Do not crush or chew the tablet, as this may affect its efficacy.


5. Missed Dose: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double up on doses.


6. Regular Check-ups: Attend regular appointments with your healthcare provider to monitor your liver function and overall health while on BARACLUDE.


7. Stay Hydrated: Drink plenty of fluids while taking this medication to help reduce the risk of dehydration.


8. Do Not Stop Abruptly: Do not stop taking BARACLUDE without consulting your doctor, as this may lead to a worsening of your condition or withdrawal symptoms.


9. Report Side Effects: Contact your healthcare provider if you experience any unusual symptoms or side effects, such as severe fatigue, jaundice (yellowing of skin or eyes), or abdominal pain.


10. Store Properly: Keep BARACLUDE at room temperature, away from moisture and heat. Ensure it is out of reach of children.

Adhering to these guidelines will help you use BARACLUDE safely and effectively. Always prioritize communication with your healthcare provider for any concerns or questions regarding your treatment.