ATRIPLA 600/200/300 (Efavirenz/Emtricitabine/Tenofovir disoproxil fumarate)

ATRIPLA is a combination medication that includes Efavirenz, Emtricitabine, and Tenofovir disoproxil fumarate, which are essential components in the treatment of HIV-1 infection. This once-daily oral medication is designed for adults and certain pediatric patients, providing a simplified regimen that enhances adherence to therapy.

The individual components of ATRIPLA work synergistically to inhibit the replication of the HIV virus:

• Efavirenz: A non-nucleoside reverse transcriptase inhibitor (NNRTI) that blocks reverse transcriptase, an enzyme crucial for HIV replication.


• Emtricitabine: A nucleoside reverse transcriptase inhibitor (NRTI) that interferes with the viral reverse transcriptase, preventing the virus from replicating.


• Tenofovir disoproxil fumarate: Another NRTI that disrupts the viral replication process by incorporating itself into viral DNA.

ATRIPLA is known for its efficacy in reducing viral load and improving immune function, making it a cornerstone in HIV treatment. Patients may experience improved quality of life due to the effectiveness of this therapy. However, it is essential for users to be aware of potential side effects, which can include dizziness, insomnia, and rash. Regular monitoring and consultations with healthcare providers are vital to ensure the best outcomes.

Overall, ATRIPLA represents a significant advancement in the management of HIV, offering a convenient and effective solution for those living with the virus.

• Efavirenz


• Emtricitabine


• Tenofovir disoproxil fumarate

ATRIPLA is a prescription medication that combines three antiretroviral drugs: Efavirenz, Emtricitabine, and Tenofovir disoproxil fumarate. It is used to treat HIV-1 infection in adults and certain pediatric patients. Follow these instructions carefully to ensure effective treatment.

1. Take ATRIPLA exactly as prescribed by your healthcare provider. Do not take more or less than the recommended dosage.




2. It is important to take ATRIPLA on an empty stomach, preferably at bedtime. This helps to minimize potential side effects and enhances absorption of the medication.




3. Swallow the tablet whole with a glass of water. Do not chew or crush the tablet, as this may affect how the medication works.




4. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.




5. Regularly monitor your health by attending follow-up appointments with your healthcare provider. They will check your HIV viral load and overall health to ensure the medication is working effectively.




6. Be aware of potential side effects, which may include dizziness, insomnia, rash, or gastrointestinal issues. If you experience severe side effects, contact your healthcare provider immediately.




7. Inform your healthcare provider about any other medications you are taking, as ATRIPLA can interact with other drugs.




8. Avoid alcohol and recreational drugs while taking ATRIPLA, as they can interfere with the effectiveness of the medication.




9. Continue taking ATRIPLA even if you feel well, as stopping the medication can lead to an increase in viral load and resistance to treatment.




10. Store ATRIPLA at room temperature, away from moisture and heat. Keep it out of reach of children and pets.

Always consult your healthcare provider for personalized advice and to address any questions or concerns regarding your treatment with ATRIPLA.