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JEVTANA 60mg/1.5 ml Vial (Cabazitaxel)
$8,397.94
Active Ingredient : Cabazitaxel
Meta description: Discover JEVTANA 60mg/1.5 ml Vial (Cabazitaxel), an effective treatment option for metastatic castration-resistant prostate cancer, designed to improve patient outcomes and enhance quality of life.
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Dispensing Country : India
JEVTANA 60mg/1.5 mL Vial contains Cabazitaxel, a chemotherapy medication used primarily in the treatment of advanced prostate cancer. It is specifically indicated for patients who have previously been treated with docetaxel and whose cancer has progressed despite this treatment. Cabazitaxel works by inhibiting cell division, thereby slowing the growth and spread of cancer cells.
This medication is administered intravenously by a healthcare professional, typically in a clinical setting. The dosage and treatment schedule are determined by the patient’s condition, overall health, and response to therapy. It is often used in combination with prednisone or another corticosteroid to enhance its effectiveness and manage potential side effects.
- Key Indication: Treatment of metastatic castration-resistant prostate cancer (mCRPC) in patients previously treated with docetaxel.
- Mechanism of Action: Cabazitaxel is a microtubule inhibitor that disrupts cancer cell division and growth.
- Administration: Intravenous infusion, usually given over one hour every three weeks.
- Common Side Effects: Include neutropenia, anemia, fatigue, diarrhea, nausea, and peripheral neuropathy. Regular monitoring of blood counts is essential to manage risks such as infections.
- Precautions: Patients should be closely monitored for hypersensitivity reactions, severe neutropenia, and gastrointestinal toxicity. Premedication with antihistamines, corticosteroids, and antiemetics is often recommended to reduce adverse effects.
- Storage: The vials should be stored in the refrigerator at 2°C to 8°C (36°F to 46°F) and protected from light. Unopened vials are stable until the expiration date printed on the packaging.
JEVTANA is a vital option for patients with advanced prostate cancer who have limited treatment alternatives. However, it requires careful administration and monitoring to ensure patient safety and optimal therapeutic outcomes. Always consult a healthcare provider for personalized medical advice and treatment plans.
- Cabazitaxel
- Polysorbate 80
- Citric Acid
- Ethanol
- Water for Injection
JEVTANA 60mg/1.5 ml Vial (Cabazitaxel) is a chemotherapy medication used to treat prostate cancer. It is administered intravenously by a healthcare professional in a clinical setting. Before administration, the patient’s blood counts and liver function should be assessed to ensure safe use. The prescribed dose is determined by the healthcare provider based on the patient’s body surface area and overall health condition.
To prepare the solution for infusion, the healthcare professional must dilute the contents of the vial with sterile 5% glucose solution or 0.9% sodium chloride solution. The appropriate amount of diluent is added to achieve the required concentration for administration. The solution should be gently mixed to ensure proper dilution and inspected for any particles or discoloration before use. If any abnormalities are observed, the solution should not be used.
Before administration, premedication is typically given to reduce the risk of allergic reactions and hypersensitivity. This may include antihistamines, corticosteroids, and H2 blockers. The infusion is then administered slowly over one hour using an intravenous line. During the infusion, the patient should be monitored closely for any signs of adverse reactions, such as fever, chills, or difficulty breathing.
After the infusion, the patient should continue to be monitored for any delayed side effects, such as low blood cell counts, diarrhea, or fatigue. Regular follow-up appointments are necessary to assess the response to treatment and manage any side effects. Proper handling and disposal of the medication and any used materials are essential to prevent contamination or exposure to others.
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